Evaluation of Salivary Lipid Peroxidation in Paan Users

Background: One known risk factor for oral cancer is chewing smokeless tobacco, which common in southeastern Iran. Smokeless tobacco-related complications can be evaluated by assessing parameters of oxidative stress. Objectives: This study salivary malondialdehyde (MDA) levels paan users and compared them with nonusers. Patients Methods: In this study, saliva was collected from 50 nonusers referred to the Zahedan Dental School Zahedan, Salivary MDA assessed based on standard biochemical methods, data were analyzed using t-test, chi-squared tests analysis variance. Results: controls, mean 2.19 ± 1.05 1.24 0.62 (nmol/mL), respectively, both groups showed significant differences (P < 0.001). The daily consumption duration significantly related concentration Conclusions: users, concentrations higher. increased more quantities a extended time.